ABSTRACT
Several plants have been selected based on their use in traditional systems of medicine, and research has identified a number of natural compounds that could act as Nootropicagents. In this study a herbal product Intellan QvXmft% CenteHa asiatica, Bacopa monniera, Coriandum sativum, Amomum subulatum, Emblica officinalis and another product Cytacon [Cyanocobalamine] were selected The study was designed on animal models to explore the effects on different parameters. For this the animals were given chronic dosing for 6-8 weeks during and after which the parameters were observed to determine their effects. The purpose of focusing on such formulations is to do hematological screening in long-term use
The hematological parameter included hemoglobin/HCT, total leucocyte count, platelets. The lymphocytes and the monocytes counts were increased significantly by intellan, while cyanocobalamine increases RBC counts, platelet counts, monocyte counts, hematocrit etc significantly
The SGPT, SGOT were found increased in both of these drugs
ABSTRACT
Essential metalloelements are usually present in the human body as low - molecular weight protein complexes and are required for various vital physiological and metabolic functions. The bioavailability of these elements depends on their absorption from food sources. Their lower or higher amounts adversely affect the biological functions. Iron [II] and zinc [II] complexes of twelve different amino acids, were synthesized and evaluated for their in - vivo absorption in rabbits. All the metal amino acid - complexes showed more absorption as compared to the respective inorganic salts. The iron [II] and zinc [II] phenylalaninates, leucinates and histidinates were more readily absorbed and showed higher metal concentration in sera as compared to the rest of metal - amino acid complexes. The phenylalaninates showed the highest absorption followed by leucinates and histidinates